Galileo was an unmanned spacecraft sent by NASA to study the planet Jupiter and its moons. Named after the astronomer and Renaissance pioneer Galileo Galilei, it was launched on October 18, 1989 by the Space Shuttle Atlantis on the STS-34 mission. It arrived at Jupiter on December 7, 1995, a little more than six years later, via gravitational assist flybys of Venus and Earth.

Despite antenna problems, Galileo conducted the first asteroid flyby, discovered the first asteroid moon, was the first spacecraft to orbit Jupiter, and launched the first probe into Jupiter's atmosphere.

On September 21, 2003, after 14 years in space and 8 years of service in the Jovian system, Galileo's mission was terminated by sending the orbiter into Jupiter's atmosphere at a speed of nearly 50 kilometres per second to avoid any chance of it contaminating local moons with bacteria from Earth. Of particular concern was the ice-crusted moon Europa, which, thanks to Galileo, scientists now suspect harbors a salt water ocean beneath its surface.